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| 产地 | |
| 品牌 | 国产 |
| 货号 | K000012M |
| 用途 | 科研实验 |
| 英文名称 | |
| 包装规格 | |
| 纯度 | % |
| CAS编号 | |
| 保质期 | 一年 |
| 是否进口 | 否 |
| 宿主 | Mouse |
|---|---|
| 英文名称 | Anti-CBX3 Monoclonal Antibody |
| 别名 | HECH;HP1-GAMMA;HP1Hs-gamma |
| 应用 | WB IF IP IHC |
| 稀释比例 | WB 1:1000. ICC 1:200. |
| 交叉反应 | Human Mouse Rat Monkey Hamster |
| 蛋白分子量 | 21kDa |
| Gene ID | 11335 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | Purified recombinant human CBX3 protein fragments expressed in E.coli. |
| 性状 | 液体 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q13185 |
| 克隆号 | 5G10-F7-A12 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] |
注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
