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产地 | |
品牌 | 国产 |
货号 | 92326 |
用途 | 科研实验 |
英文名称 | UACA Antigen (Recombinant Protein) |
包装规格 | |
纯度 | % |
CAS编号 | |
保质期 | 一年 |
是否进口 | 否 |
中文名称:UACA 抗原(重组蛋白)
英文名称:UACA Antigen (Recombinant Protein)
别 名:uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING
储 存:冷冻(-20℃)
相关类别:抗原
概 述 Fusion protein corresponding to C terminal 200 amino acids of human UACA 技术规格
Full name: | uveal autoantigen with coiled-coil domains and ankyrin repeats |
Synonyms: | NUCLING |
Swissprot: | Q9BZF9 |
Gene Accession: | BC113407 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). |