Recombinant Human NGF-β 450-01 Peprotech细胞因子报价

 

 

Catalog Number:

450-01

Synonyms:

NGF-β

Description:

β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.

AA Sequence:

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED ₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10 ⁶ units/mg.

 

 

Recombinant Human NGF-β 450-01 Peprotech细胞因子报价

 

 

Cross Reactivity:

Chicken, Hamster, Mouse, Rat, Human, Leech

Research Interests:

	Angiogenesis/ Cardiovascular		Chemotaxis
	Diabetes / Weight Regulation		Inflammation
	Neurobiology		Stem Cells & Differentiation
	Wound Healing

 

 

Country of Origin:

 

USA

 

 

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