优势北京Peprotech 210-13 Recombinant Murine IL-13细胞因子价格

品名：Recombinant Murine IL-13 

货号：210-13

规格：2UG/10UG

品牌：Peprotech

        北京杰辉博高生物技术有限公司在广大科研用户的帮助和支持下，经过多年不懈的努力，已成为国内生命科学试剂的国际运营商之一，代理许多国际先进水平的高科技产品，包括分子生物学、细胞生物学、免疫学、诊断，仪器仪表等多个研究及应用领域。。

Catalog Number:

210-13

Synonyms:

NC300 (Human) P600 (Murine)

Description:

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.

AA Sequence:

MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED ₅₀ as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 10 ⁵ units/mg.

Cross Reactivity:

Human, Mouse