Recombinant Human IL-1β

Catalog Number:

200-01B

Synonyms:

Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Description:

IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.

AA Sequence:

APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED ₅₀ as determined by the dose-dependent stimulation of thymidine uptake by murine D10S cells is ≤ 1.0 pg/ml, corresponding to a specific activity of ≥ 1 x 10 ⁹ units/mg.

现货促销Recombinant Human IL-1β 200-01B Peprotech细胞因子报价

联系电话： 010-57269778

Cross Reactivity:

Frog, Monkey, Mouse, Rabbit, Rat, Sheep, Human, Mouse + Chicken, Cow, Human + Rat, Pig

Research Interests:

	Angiogenesis/ Cardiovascular		Cancer
	Diabetes / Weight Regulation		Immune System
	Inflammation		Neurobiology
	Proliferation		Stem Cells & Differentiation
	Wound Healing		Allergy
	Transplantation

Country of Origin:

USA Recombinant

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