Recombinant Murine FGF-acidic

Catalog Number:

450-33A

Synonyms:

Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta

Description:

FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

AA Sequence:

MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Source:

E.coli

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

Assay #1: The ED ₅₀ as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 10 ⁶ units/mg.

Assay #2: The ED ₅₀ was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.2 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 5 x 10 ⁶ units/mg.

特价北京Recombinant Murine FGF-acidic 450-33A ，Peprotech细胞因子报价

Cross Reactivity:

Mouse, Human

Research Interests:

	Angiogenesis/ Cardiovascular		Cancer
	Cell Culture		FGF Superfamily
	Neurobiology		Proliferation
	Stem Cells & Differentiation		Wound Healing

Country of Origin:

USA

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