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热销Peprotech Recombinant Human IL-10细胞因子200-10说明书
产品编号:
200-10
别名:
B-TCGF,CSIF,TGIF
描述:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6 kDa protein of 161 amino acid residues.
氨基酸序列:
MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by the dose-dependent co-stimulation (with human IL-4) of MC/9 cells. The ED 50 was found to be ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10 5 units/mg.
交叉反应:
Bacteria, Monkey, Mouse, Virus
研究领域:
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AIDS/ HIV | ![]() |
癌症 |
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免疫系统 | ![]() |
炎症 |
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神经生物学 | ![]() |
干细胞及分化 |
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过敏 | ![]() |
移植 |
原产国:
USA
仅用于研究。不适用于诊断或治疗。
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