中文别名
盐酸苄唑啉.盐酸妥拉唑林7-乙基-10羟基喜树碱伊立替康杂质B7-乙基-10-羟基喜树伊立替康相关杂质B7-乙基-10-羟基喜树碱(SN-38)7-乙基-10-羟基喜树碱 1G乙酰甘草次酸(S)-4,9-二羟基-4,11-二乙基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-B]喹啉-3,14(4H,12H)-二酮7-乙基-10-羟基喜树碱(替康类)喜树碱7-乙基-10-羟基杂质
英文别名
7-Ethyl-10-hydroxycamptothecineSN38MFCD06762720SN-381H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione7-Ethyl-10-Hydroxycamptothecin(SN-38)7-Ethyl-10-hydroxy-CPT (Camptothecine), SN-387-10-hydroxycamptothecin(4S)-4,9-Dihydroxy-4α,11-diethyl-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dioneIrinotecan Related Compound B (10 mg) ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)(4S)-4,9-Dihydroxy-4,11-diethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dioneEHCPTSN 38(7-Ethyl-10-hydroxycaMptothecin)
CAS
86639-52-3
Inchi
InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1
InChIkey
FJHBVJOVLFPMQE-QFIPXVFZSA-N
Canonical Smiles
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O
国际化联命名
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
密度：1.51
熔点：217 °C
沸点：810.3 °C at 760 mmHg
折射率：21.5 ° (C=0.2, THF)
闪光点：443.8 °C
蒸汽压：0.0±3.0 mmHg at 25°C
PSA：101.65000
logP：2.34760
溶解度：DMSO: soluble1mg/mL
外观：淡黄色固体
存储：-20 °C 冷藏
化学性质：Light-Yellow Solid
颜色：Yellow powder
酸度系数（pka）：9.13±0.40(Predicted)
溶解性：未确定
存储温度：-20°C
