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| 产地 | 国产 |
| 品牌 | Solarbio |
| 货号 | IC7670 |
| 用途 | 抑制剂 |
| 包装规格 | 100mg |
| CAS编号 | 64-86-8 |
| 纯度 | 98% |
| 是否进口 | 否 |
| CAS | 64-86-8 |
| 英文名称 | Colchicine |
| 纯度 | ≥98% |
| 描述 | Colchicine是微管蛋白抑制剂和微管干扰剂。(Colchicine is a tubulin inhibitor and microtubule disruptor.) |
| 靶点 | Microtubule/Tubulin |
| 通路 | Cytoskeleton |
| 规格 | 100mg |
| 单位 | 瓶 |
熔点：150-160℃
沸点：RELATIVE DENSITY
折射率：1.584
闪光点：392.9°C
蒸汽压：3.2X10-11 mm Hg at 25 °C (est)
PSA：83.09000
logP：3.26250
溶解度：H2O: 10?mg/mL
外观：黄色粉末
存储：
棕色玻璃瓶闭光密闭包装。贮存于阴凉干燥处。
化学性质：It is pale yellow crystal or crystalline powder with bitter taste and the color being changed upon exposure to light.. M.p. is 157 ℃ (recrystallized from ethyl acetate), specific rotation [α] 17D-429 ° (1.72%, water),-121° (0.9%, chloroform). It has the maximum absorption wavelengths being 243nm and 350.5 nm in ethanol. This product is easily soluble in water, ethanol and chloroform, soluble in benzene and ether, but insoluble in petroleum ether. The 0.5% solution of this product is acidic. LD50 (mouse, intraperitoneal) is 6.1mg/kg.
颜色：浅黄色结晶或结晶性粉末
分解：When heated to decomposition, colchicine emits toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides.
气味：Odorless or nearly so
pH值：pH of 0.5% solution: 5.9
物理属性：浅黄色结晶或结晶性粉末，有味，味苦，见光变色。Mp157℃(乙酸乙酯重结晶)，比旋光度[α]17D-429°(1.72%，水)、-121°(0.9%，氯仿)，在乙醇中 吸收波长为243nm和350.5nm。本品易溶于水、乙醇和氯仿，溶于苯和乙醚，不溶于石油醚，0.5%的本品溶液呈弱酸性。LD50(小鼠、腹腔) 6.1mg/kg。
酸度系数（pka）：12.36(at 20℃)
溶解性：易溶于水、乙醇和氯仿，溶于苯和乙醚，不溶于石油醚
光谱特性：Specific optical rotation: -429 at 17 deg C/D (water, 1.72%); -121 deg at 17 deg c/d (concentration by volume = 0.9 g in 100 ml chloroform); max absorption (95% ethanol): 350.5 nm (log epsilon = 4.22), 243 nm (log epsilon = 4.47)
IR: 17152 (Sadtler Research Laboratories Prism Collection)
UV: 5410 (Sadtler Research Laboratories Spectral Collection)
MASS: 35758 (NIST/EPA/MSDC Mass Spectral Database, 1990 Version)
稳定性：Stable. Light sensitive. Incompatible with strong oxidizing agents.
存储温度：Poison room
