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CAS
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2239273-34-6
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英文名称
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AB928
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别名
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AB928
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纯度
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≥98%
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分子式
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C23H22N8O
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分子量
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426.47
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外观（性状）
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Off-white to light yellow Solid
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储存条件
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Powder:2-8℃，2 years;In solvent(母液):-20℃，1 month; -80℃，6 months
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溶解性
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Soluble in DMSO ≥5mg/mL(Need ultrasonic)
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描述
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AB928 是一种选择性的腺苷受体 (A2aR/A2bR) 双拮抗剂。(AB928 is a selective adenosine receptor (A2aR/A2bR) dual antagonist. AB928 has immunomodulatory and antitumor activities.)
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靶点
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Adenosine Receptor(A2aR/A2bR)
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通路
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GPCR & G Protein
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规格
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1mg
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单位
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瓶
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中文名称：化合物AB928
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英文名称：AB928 | Adenosine Receptor
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CAS No.：2239273-34-6
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分子式：C23H22N8O同分异构体
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分子量：426.5
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类别：生化与分子生物试剂 其他试剂 合成材料中间体
中文别名
3-(2-氨基-6-(1-((6-(2-羟丙基)吡啶-2-基)甲基)-1H-1,2,3-三唑-4-基)嘧啶-4-基)-2-甲基苯腈3-[2-氨基-6-[1-[[6-(1-羟基-1-甲基乙基)-2-吡啶基]甲基]-1H-1,2,3-三唑-4-基]-4-嘧啶基]-2-甲基苯腈
英文别名
AB 928)AB928(AB-928Benzonitrile, 3-[2-amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methyl-3-(2-amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrileZB1610AB928 (AB-928Etrumadenant (AB928)AB928,inhibit,AB-928,AB 928,P1 receptor,Adenosine Receptor,InhibitorAB928AB-928BS-16547MFCD322630403-[2-Amino-6-(1-{[6-(2-hydroxy-2-propanyl)-2-pyridinyl]methyl}-1H-1,2,3-triazol-4-yl)-4-pyrimidinyl]-2-methylbenzonitrile3-[2-amino-6-(1-{[6-(2-hydroxypropan-2-yl)pyridin-2-yl]methyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl]-2-methylbenzonitrile3-[2-amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methyl-benzonitrile
CAS
2239273-34-6
Inchi
InChI=1S/C23H22N8O/c1-14-15(11-24)6-4-8-17(14)18-10-19(28-22(25)27-18)20-13-31(30-29-20)12-16-7-5-9-21(26-16)23(2,3)32/h4-10,13,32H,12H2,1-3H3,(H2,25,27,28)
InChIkey
BUXIAWLTBSXYSW-UHFFFAOYSA-N
Canonical Smiles
CC1=C(C=CC=C1C2=CC(=NC(=N2)N)C3=CN(N=N3)CC4=NC(=CC=C4)C(C)(C)O)C#N
国际化联命名
3-[2-amino-6-[1-[[6-(2-hydroxypropan-2-yl)pyridin-2-yl]methyl]triazol-4-yl]pyrimidin-4-yl]-2-methylbenzonitrile
