|
CAS
|
125-04-2
|
|
英文名称
|
Hydrocortisone sodium succinate
|
|
中文名称
|
氢化可的松琥珀酸钠
|
|
纯度
|
≥98%
|
|
分子式
|
C25H33NaO8
|
|
分子量
|
484.51
|
|
外观（性状）
|
White to off-white Solid
|
|
储存条件
|
Powder:-20℃，2years;Insolvent(母液):-20℃，1month;-80℃，6months
|
|
溶解性
|
Soluble in DMSO ≥5mg/mL
|
|
描
|
Hydrocortisone sodium succinate 可与糖皮质激素受体(glucocorticoid receptor) 结合。(It has been reported that Hydrocortisone sodium succinate has a significant inhibitory effect on IL-6 bioactivity. Hydrocortisone sodium succinate can bind to the glucocorticoid receptor to initiate the transcription of anti-inflammatory and immunosuppressive mediators.)
|
|
靶点
|
IL-6;glucocorticoid receptor
|
|
通路
|
Immunology & Inflammation;Endocrinology & Hormones;GPCR & G Protein
|
|
规格
|
100mg
|
|
单位
|
瓶
|
