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CAS
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2225819-06-5
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英文名称
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BAY-2402234
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纯度
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≥98%
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分子式
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C21H18ClF5N4O4
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分子量
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520.84
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外观（性状）
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Solid
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储存条件
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Powder : 2-8℃， 2 years;In solvent(母液): -20℃， 1 month; -80℃， 6 months
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溶解性
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Soluble in DMSO(Need ultrasonic)
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描述
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BAY-2402234 是一个选择性的、二氢乳清酸脱氢酶 (DHODH) 的抑制剂。(BAY-2402234 is a selective inhibitor of dihydrowhey dehydrogenase (DHODH).)
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靶点
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Dihydroorotate dehydrogenase (DHODH)
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通路
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Metabolic Enzyme&Protease
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规格
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5mg
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单位
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瓶
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中文别名
(S)-N-(2-氯-6-氟苯基)-4-(4-乙基-3-(羟甲基)-5-氧代-4,5-二氢-1H-1,2,4-三唑-1-基)-5-氟-2-((1,1,1-三氟丙烷-2-基)氧基)苯甲酰胺化合物BAY-2402234
英文别名
N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamideN-(2-Chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoro-2-propanyl]oxy}benzamide(S)-N-(2-Chloro-6-fluorophenyl)-4-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)benzamideMFCD31692414BAY-2402234Benzamide, N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-4,5-dihydro-3-(hydroxymethyl)-5-oxo-1H-1,2,4-triazol-1-yl]-5-fluoro-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]-N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzamideinhibit,BAY 2402234,Inhibitor,DHODH,DNA/RNA Synthesis,BAY2402234,BAY-2402234,Dihydroorotate DehydrogenaseORLUDODSTAT
CAS
2225819-06-5
Inchi
InChI=1S/C21H18ClF5N4O4/c1-3-30-17(9-32)29-31(20(30)34)15-8-16(35-10(2)21(25,26)27)11(7-14(15)24)19(33)28-18-12(22)5-4-6-13(18)23/h4-8,10,32H,3,9H2,1-2H3,(H,28,33)/t10-/m0/s1
InChIkey
KNVJMHHAXCPZHF-JTQLQIEISA-N
Canonical Smiles
CCN1C(=NN(C1=O)C2=C(C=C(C(=C2)O[C@@H](C)C(F)(F)F)C(=O)NC3=C(C=CC=C3Cl)F)F)CO
国际化联命名
N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzamide
