CAS
|
189950-66-1
|
浓度
|
≥97%
|
英文名称
|
Ac-DEVD-pNA
|
分子式
|
C26H34N6O13
|
分子量
|
638.58
|
外观(性状)
|
White to off-white Solid
|
储存条件
|
Powder : -20℃, 1 year;In solvent(母液): -20℃, 1 month; -80℃, 6 months
|
溶解性
|
Soluble in DMSO
|
MDL
|
MFCD00792707
|
SMILES
|
O=C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O)[C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O
|
描述
|
Ac-DEVD-pNA 是 caspase-3 和相关半胱氨酸蛋白酶的配体。(Ac-DEVD-pNA is a ligand for caspase-3 and related cysteine proteases.)
|
靶点
|
caspase-3;Cysteine Protease
|
通路
|
Apoptosis;Metabolic Enzyme&Protease
|
生物活性
|
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.[1]
|
数据来源文献
|
[1]. Talanian RV, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997 Apr 11;272(15):9677-82.
|
规格
|
5mg
|
单位
|
瓶
|