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CAS
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103476-89-7
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中文名称
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亮抑酶肽
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英文名称
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Leupeptin
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别名
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亮抑蛋白酶肽;LeupeptinHemisulfate
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纯度
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≥98%
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分子式
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C20H38N6O4·1/2H2SO4
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分子量
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475.59
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO
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MDL
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MFCD00037012
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EC
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EINECS 600-443-5
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InChIKey
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CIPMKIHUGVGQTG-VFFZMTJFSA-N
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InChI
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InChI=1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
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PubChem CID
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2733491
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SMILES
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O=C[C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N.[0.5H2SO4]
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描述
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Leupeptin是一种可透过膜的巯基蛋白酶抑制剂,可抑制 Cathepsin B, Cathepsin H 和 Cathepsin L,并损害两性溶酶体的融合。(Leupeptin is a membrane-permeable thiol protease inhibitor that inhibits Cathepsin B, Cathepsin H and Cathepsin L and impairs amphiphilic lysosome fusion.)
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靶点
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Cathepsin;Serine Protease
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通路
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Metabolic Enzyme/Protease
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规格
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1mg 5mg 10mM*1mL (in DMSO) 10mM*1mL in Water
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单位
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瓶
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