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CAS
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71486-22-1
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中文名称
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长春瑞滨
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英文名称
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Vinorelbine
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纯度
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HPLC≥98%
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分子式
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C45H54N4O8
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分子量
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778.93
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO ≥10mg/mL
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描述
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Vinorelbine是一种长春花生物碱，可以与微管蛋白结合并阻止有丝分裂纺锤体的形成，导致中期细胞生长停滞。(Vinorelbine is a vinca alkaloid that binds to tubulin and prevents the formation of mitotic spindles, leading to metaphase tumor cell growth arrest.)
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靶点
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Microtubule/Tubulin
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通路
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Cytoskeleton
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规格
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10mg 20mg
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单位
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瓶
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中文名称：长春瑞宾
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英文名称：Vinorelbine
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CAS No.：71486-22-1
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分子式：C45H54N4O8同分异构体
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分子量：778.947
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类别：对照品 其它 标准物质
中文别名
长春瑞滨长春碱杂质K诺威本VINORELBINE 长春瑞滨长春瑞滨(去甲长春花碱,诺维本,民诺宾,盖诺,异长春花碱)去甲长春花碱,诺维本,民诺宾,盖诺,异长春花碱威诺瑞滨去甲长春花碱
英文别名
aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2Β,3Β,4Β,5α,12Β,19α)-Quinoline,8-(methylthio)-5-(nonylthio)Methyl (2Β,3Β,4Β,5α,12Β,19α)-4-acetoxy-15-[(12S)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0.0]octadeca-3(11),4,6,8,15-pentaen-12-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylatevinorelbene5'-noranhydrovinblastine5-Nonylthio-8-methylthio-chinolin3',4'-didehydro-4'-desoxy-8'-norvincaleucoblastineAspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methMethyl (2Β,3Β,4Β,5α,12Β,19α)-4-acetoxy-15-[(12S)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0.0]octadeca-3(11),4,6,8,15-pentaen-12-yl]-3-hydroxy-16-methox y-1-methyl-6,7-didehydroaspidospermidine-3-carboxylatevinorebline8-methylsulfanyl-5-nonylsulfanyl-quinolineyl ester, (2Β,3Β,4Β,5α,12Β,19α)-nor-5’-anhydrovinblastinevinorelbine D-tartrateCL069ANX-530, KW-2307, 5'-Noranhydrovinblastine3’,4’-didehydro-4’-deoxy-c’-norvincaleukoblastinAspidosperMidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8CS-404展开∨
CAS
71486-22-1
Inchi
InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3
InChIkey
GBABOYUKABKIAF-UHFFFAOYSA-N
Canonical Smiles
CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC
