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CAS
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55-56-1
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中文名称
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氯己定
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英文名称
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Chlorhexidine
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别名
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洗必泰碱；洗必泰
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纯度
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≥98%
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分子式
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C22H30Cl2N10
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分子量
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505.45
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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EC
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EINECS 200-238-7
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MDL
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MFCD00009673
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SMILES
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N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N
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描述
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Chlorhexidine是一种 化合物。(Chlorhexidine is an antibacterial compound.)
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靶点
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Bacterial
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通路
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Anti-infection
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生物活性
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Chlorhexidine is an antibacterial used as an antiseptic and for other applications. Chlorhexidine is used to clean the skin after an injury, before surgery, or before an injection. Chlorhexidine is also used to clean the hands before a procedure[1].
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In Vivo
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Chlorhexidine gluconate (ip) reduces postoperative intra-abdominal infection in mice at the end of colon surgery[1].
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动物实验
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Animal Model: One hundred and eighty male Imprinting Control Region (ICR) mice at 6 to8-wk-old (body weight, 25 ± 3 g) were randomized to six groups; Dosage: Chlorhexidine gluconate 0.05%, and Chlorhexidine gluconate 0.025%; Administration: One-time intraperitoneal injection.[1].
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数据来源文献
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[1]. Wael E Shams, et al. Peritoneal Lavage Using Chlorhexidine Gluconate at the End of Colon Surgery Reduces Postoperative Intra-Abdominal Infection in Mice. J Surg Res. 2015 May 1;195(1):121-7.
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规格
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100mg 10mM*1mL in DMSO 250mg 500mg
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单位
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瓶
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