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CAS
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121123-17-9
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中文名称
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头孢丙烯一水
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英文名称
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Cefprozil Monohydrate
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别名
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头孢布烯；头孢曲唑一水合物
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纯度
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≥98%
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分子式
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C18H19N3O5S·H2O
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分子量
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407.44
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外观（性状）
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White to light yellow Solid
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储存条件
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Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00911719
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SMILES
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O=C(O)C(N1[C@]([H])([C@@H](C1=O)NC([C@@H](C2=CC=C(O)C=C2)N)=O)SC3)=C3/C=C/C.[H]O[H]
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描述
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是 代头孢菌素类抗生素。(It is a second-generation cephalosporin antibiotic.)
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靶点
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Bacterial
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通路
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Anti-infection
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生物活性
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Cefprozil is an orally active cephalosporin which has demonstrated activity against a wide range of organisms in vitro. [1]
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In Vitro
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Cefprozil is particularly active against the Gram-positive organisms Streptococcus pyogenes, pneumoniae and agalactiae and against methicillin-susceptible Staphylococcus aureus. Strains of methicillin-resistant S. aureus are not susceptible to cefprozil. Cefprozil is also moderately active against Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, many Enterobacteriaceae and certain anaerobic organisms, and is relatively stable to hydrolysis by a number of beta-lactamases.[1]
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数据来源文献
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[1]. Wiseman LR, Benfield P. Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential. Drugs. 1993 Feb;45(2):295-317.
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规格
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5mg 10mg
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单位
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瓶
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