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CAS
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546-88-3
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中文名称
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乙酰氧肟酸
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英文名称
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Acetohydroxamic Acid
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别名
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乙酰异羟肟酸；菌石通
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纯度
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≥98%
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分子式
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C2H5NO2
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分子量
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75.07
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO ≥1mg/mL
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EC
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EINECS 208-913-8
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MDL
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MFCD00009994
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InChIKey
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RRUDCFGSUDOHDG-UHFFFAOYSA-N
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InChI
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InChI=1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)
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PubChem CID
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1990
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SMILES
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CC(O)=NO
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描述
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Acetohydroxamic Acid是一种有效的不可逆细菌和植物尿素酶抑制剂。(Acetohydroxamic Acid is a potent irreversible bacterial and plant urease inhibitor.)
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靶点
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Bacterial
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通路
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Anti-infection
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生物活性
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Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection. Target: Urease Acetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.[1]
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数据来源文献
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[1]. Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52(1):76-82.
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规格
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100mg 500mg
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单位
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瓶
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