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CAS
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7481-89-2
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中文名称
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扎西他滨
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英文名称
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Zalcitabine
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别名
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双脱氧胞嘧啶核苷
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纯度
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≥98%
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分子式
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C9H13N3O3
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分子量
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211.22
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外观（性状）
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White to yellow Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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EC
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EINECS 620-762-3
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MDL
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MFCD00012188
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InChIKey
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WREGKURFCTUGRC-POYBYMJQSA-N
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InChI
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InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1
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PubChem CID
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24066
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SMILES
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NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1
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描述
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是有效的核苷类似物逆转录酶抑制剂,用于相关研究。(It is a potent nucleoside analog reverse transcriptase inhibitor for the study of HIV infection.)
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靶点
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HIV;Reverse Transcriptase
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通路
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Anti-infection
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生物活性
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Zalcitabine是有效的核苷类似物逆转录酶抑制剂，
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In Vitro
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数据来源文献
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[1]. Adkins JC, et al. Zalcitabine. An update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection.Drugs. 1997 Jun;53(6):1054-80
[2]. Jin MJ, et al. Interaction of zalcitabine with human organic anion transporter 1. Pharmazie. 2006 May;61(5):491-2.
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规格
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25mg 50mg 100mg
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单位
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瓶
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