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CAS
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23541-50-6
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中文名称
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盐酸柔红霉素
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英文名称
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Daunorubicin Hydrochloride
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别名
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盐酸佐柔比星; 盐酸正丁霉素; RP-13057
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纯度
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HPLC≥98%
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分子式
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C27H29NO10·HCl
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分子量
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563.98
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外观（性状）
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Red Solid
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储存条件
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Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO ≥10mg/mL
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EC
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EINECS 245-723-4
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MDL
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MFCD04974507
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InChIKey
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GUGHGUXZJWAIAS-QQYBVWGSSA-N
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InChI
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InChI=1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
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PubChem CID
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62770
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SMILES
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O=C(C(C(OC)=CC=C1)=C1C2=O)C3=C2C(O)=C(C[C@@](O)(C(C)=O)C[C@@H]4O[C@@]5([H])C[C@H](N)[C@H](O)[C@H](C)O5)C4=C3O.[H]Cl
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描述
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Daunorubicin HCl抑制DNA和RNA合成。是 topoisomerase II 的抑制剂并可诱导凋亡。具有 活性,是一种抗生素。(Daunorubicin HCl inhibits DNA and RNA synthesis. It is an inhibitor of topoisomerase II and induces apoptosis. It has antibacterial activity and is an antibiotic.)
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靶点
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Antibiotic;Topoisomerase
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通路
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Anti-infection;DNA Damage/DNA Repair
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生物活性
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