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CAS
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91161-71-6
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中文名称
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特比萘芬
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英文名称
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Terbinafine Hydrochloride
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别名
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特比萘酚;盐酸特比萘芬;Terbinafine
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纯度
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HPLC≥98%
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分子式
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C21H25N
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分子量
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291.43
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外观（性状）
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White to yellow Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO ≥ 25mg/mL
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EC
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EINECS 245-385-8
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MDL
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MFCD00242672
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InChIKey
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DOMXUEMWDBAQBQ-WEVVVXLNSA-N
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InChI
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InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
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PubChem CID
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1549008
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SMILES
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CN(C/C=C/C#CC(C)(C)C)CC1=C2C=CC=CC2=CC=C1
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描述
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为烯丙胺类化合物,抑制真菌细胞麦角甾醇合成过程中的鲨烯环氧化酶,并使鲨烯在细胞中蓄积而起杀菌作用。(It is an allylamine antifungal compound, which inhibits squalene cyclooxygenase in the process of ergosterol synthesis in fungal cells, and enables squalene to accumulate in cells and play a bactericidal role.)
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靶点
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Fungal
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通路
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Anti-infection
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