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CAS
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957-68-6
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中文名称
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7-氨基头孢烷酸
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英文名称
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7-Aminocephalosporanic acid
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别名
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7-氨基头孢菌酸;7-ACS
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纯度
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HPLC≥97%
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分子式
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C10H12N2O5S
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分子量
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272.28
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00005177
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EC
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EINECS 213-485-0
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InChIKey
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HSHGZXNAXBPPDL-HZGVNTEJSA-N
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InChI
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InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
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PubChem CID
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441328
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SMILES
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O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](N)C1=O)O
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描述
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7-Aminocephalosporanic acid是有效的β-lactamase抑制剂。(7-Aminocephalosporanic acid is a potent β-lactamase inhibitor.)
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靶点
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Bacterial
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通路
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Anti-infection
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生物活性
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Deacetylation of 7-aminocephalosporanic acid (7-ACA) at position C-3 provides valuable starting material for producing semisynthetic β-lactam antibiotics. [1]
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In Vitro
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Deacetyl cephalosporins are highly valuable building blocks for the industrial production of various kinds of semisynthetic β-lactam antibiotics. These compounds are derived mainly from 7-ACA, which is obtained by chemical or enzymatic processes from cephalosporin C. [1]
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数据来源文献
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[1]. Ding JM, et al. Identification and Characterization of a New 7-Aminocephalosporanic Acid Deacetylase from Thermophilic Bacterium Alicyclobacillus tengchongensis. J Bacteriol. 2015 Nov 2;198(2):311-20.
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规格
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50mg 100mg
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