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CAS
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856867-55-5
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中文名称
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磷酸泰地唑胺
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英文名称
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Tedizolid Phosphate
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别名
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磷酸泰地唑胺
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纯度
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≥98%
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分子式
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C17H14FN6O2·H2PO4
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分子量
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450.32
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00272624
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EC
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EINECS 1592732-453-0
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InChIKey
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QCGUSIANLFXSGE-GFCCVEGCSA-N
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InChI
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InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1
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PubChem CID
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11476460
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SMILES
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O=C1O[C@@H](COP(O)(O)=O)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2
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描述
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是MAO-A和MAO-B抑制剂,具有抗革兰氏阳性菌活性。(It is a MAO-A and MAO-B inhibitor with anti-Gram-positive activity.)
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靶点
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Bacterial;MAO
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通路
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Anti-infection; Neuronal Signaling
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数据来源文献
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[1]. Antimicrob Agents Chemother. 2012 Sep;56(9):4713-7.
[2]. Choi S, et al. Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-resistant and Penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Jun 19.
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规格
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5mg 10mM*1mL in DMSO 10mg
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单位
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瓶
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