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CAS
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65277-42-1
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中文名称
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酮康唑
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英文名称
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Ketoconazole
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别名
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(±)-Ketoconazol;Extina;Xolegel
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纯度
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HPLC≥98%
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分子式
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C26H28Cl2N4O4
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分子量
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531.43
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO ≥10mg/mL
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MDL
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MFCD00058579
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EC
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EINECS 265-667-4
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InChIKey
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XMAYWYJOQHXEEK-OZXSUGGESA-N
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InChI
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InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1
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PubChem CID
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456201
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SMILES
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CC(N1CCN(C2=CC=C(OC[C@@H]3O[C@@](CN4C=CN=C4)(C5=CC=C(Cl)C=C5Cl)OC3)C=C2)CC1)=O.[relative stereochemistry]
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描述
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是经典的CYP3A4抑制剂,也是 CYP24A1的抑制剂。(Ketoconazole is an imidazole antifungal agent, a classic CYP3A4 inhibitor, and an inhibitor of CYP24A1.)
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靶点
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Fungal;Cytochrome P450
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通路
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Anti-infection
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规格
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50mg 10mM*1mL (in DMSO) 100mg
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单位
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瓶
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