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CAS
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103-90-2
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中文名称
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对乙酰氨基酚
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英文名称
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Acetaminophen
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别名
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4-乙酰胺基苯酚; 对羟基乙酰苯胺
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纯度
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HPLC≥98%
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分子式
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C8H9NO2
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分子量
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151.16
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years
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溶解性
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Soluble in Water/DMSO ≥ 5mg/mL(该产品在溶液状态不稳定,建议您现用现配/The product is unstable after dissolution. It is recommended that you use it immediately after dissolution.)
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MDL
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MFCD00002328
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EC
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EINECS 203-157-5
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InChIKey
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RZVAJINKPMORJF-UHFFFAOYSA-N
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InChI
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InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
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PubChem CID
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1983
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SMILES
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O=C(C)NC1=CC=C(O)C=C1
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描述
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Acetaminophen是选择性环氧合酶-2 (COX-2) 的抑制剂,还是一种有效的肝N-乙酰转移酶 2 (NAT2) 抑制剂。(Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.)
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靶点
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COX-2
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通路
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Immunology & Inflammation
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生物活性
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Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂[1-3]。
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IC50
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IC50: COX-2:25.8 μM[1-3]IC50: COX-1:113.7 μM ) [1-3]
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