|
CAS
|
1219168-18-9
|
|
英文名称
|
Dorsomorphin dihydrochloride
|
|
别名
|
FD5027;Dorsomorphin 2HCl;BML-275;BML-275 2HCl
|
|
纯度
|
≥98%
|
|
分子式
|
C24H25N5O·2HCl
|
|
分子量
|
472.41
|
|
外观(性状)
|
Light yellow to yellow Solid
|
|
储存条件
|
Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
|
|
溶解性
|
Soluble in Water
|
|
MDL
|
MFCD11112197
|
|
InChIKey
|
RJDVIJJQKMGPMV-UHFFFAOYSA-N
|
|
InChI
|
InChI=1S/C24H25N5O.2ClH/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20;;/h4-11,16-18H,1-3,12-15H2;2*1H
|
|
PubChem CID
|
49761481
|
|
SMILES
|
[H]Cl.[H]Cl.C12=C(C3=CC=NC=C3)C=NN1C=C(C4=CC=C(OCCN5CCCCC5)C=C4)C=N2
|
|
描述
|
Dorsomorphin Dihydrochloride是一种有效,选择性和 ATP 竞争性的 AMPK 抑制剂。(Dorsomorphin Dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor.)
|
|
靶点
|
AMPK
|
|
通路
|
PI3K/Akt/mTOR;Epigenetics
|