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CAS
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138112-76-2
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中文名称
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阿戈美拉汀
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英文名称
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Agomelatine
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别名
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N-[2-(7-甲氧基-1-萘基)乙基]乙酰胺
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纯度
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≥98%
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分子式
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C15H17NO2
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分子量
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243.3
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO ≥10mg/mL
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EC
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EINECS 629-727-7
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MDL
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MFCD00916659
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InChIKey
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YJYPHIXNFHFHND-UHFFFAOYSA-N
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InChI
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InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)
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PubChem CID
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82148
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SMILES
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CC(NCCC1=C2C=C(OC)C=CC2=CC=C1)=O
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描述
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Agomelatine是一种 MT1 和 MT2 受体的特异性激动剂。Agomelatine 还是一种选择性的 5-HT2C 受体拮抗剂。(Agomelatine is a specific agonist for the MT1 and MT2 receptors. Agomelatine is also a selective 5-HT2C receptor antagonist.)
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靶点
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Melatonin Receptor; 5-HT Receptor
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通路
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GPCR/G Protein; Neuronal Signaling
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