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CAS
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129722-12-9
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中文名称
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阿立哌唑
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英文名称
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Aripiprazole
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别名
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Abilify
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纯度
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HPLC≥98%
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分子式
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C23H27Cl2N3O2
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分子量
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448.39
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外观（性状）
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White to yellow Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00892072
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EC
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EINECS 200-835-2
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InChIKey
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CEUORZQYGODEFX-UHFFFAOYSA-N
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InChI
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InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
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PubChem CID
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60795
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SMILES
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O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1
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描述
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据报道是一种高亲和力的5-HT受体部分激动剂。(It is reported to be a high-affinity 5-HT receptor partial agonist.)
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靶点
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5-HT Receptor
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通路
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Neuronal Signaling;GPCR & G Protein
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生物活性
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Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.[1-2]
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IC50
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5-HT1A:4.2 nM(Ki) [1]
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