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CAS
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60-80-0
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中文名称
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安替比林
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英文名称
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Antipyrine
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别名
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二甲基苯基吡唑酮; ?安替吡啉
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纯度
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GC≥98%
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分子式
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C11H12N2O
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分子量
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188.23
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO
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MDL
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MFCD00003146
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EC
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EINECS 200-486-6
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InChIKey
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VEQOALNAAJBPNY-UHFFFAOYSA-N
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InChI
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InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
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PubChem CID
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2206
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SMILES
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O=C1N(C2=CC=CC=C2)N(C)C(C)=C1
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描述
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Antipyrine是一种选择性COX3抑制剂。(Antipyrine is a selective COX3 inhibitor.)
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靶点
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COX-3
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通路
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Immunology & Inflammation
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生物活性
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Antipyrine, an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.[1-2]
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数据来源文献
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[1] Kind PR, et al, J Clin Pathol, 1954, 7(4), 322-326.
[2] Soberman R, et al, J Biol Chem, 1949, 179(1), 31-42.
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规格
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10mg 10mM*1mL (in DMSO) 50mg 100mg
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单位
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瓶
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