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CAS
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12542-36-8
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中文名称
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醋酸棉酚
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英文名称
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Gossypol Acetic Acid
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别名
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棉子酚乙酸酯
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纯度
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HPLC≥98%
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分子式
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C32H34O10
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分子量
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578.61
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外观（性状）
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Light yellow to yellow Solid
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储存条件
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Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00058385
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EC
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EINECS 623-939-3
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InChIKey
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NIOHNDKHQHVLKA-UHFFFAOYSA-N
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InChI
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InChI=1S/C30H30O8.C2H4O2/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36;1-2(3)4/h7-12,33-38H,1-6H3;1H3,(H,3,4)
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PubChem CID
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227456
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SMILES
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OC1=C(C2=C(O)C(C(C=O)=C(O)C(O)=C3C(C)C)=C3C=C2C)C(C)=CC4=C(C(C)C)C(O)=C(O)C(C=O)=C41.O=C(O)C
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描述
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Gossypol Acetic Acid是一些脱氢酶（如乳酸脱氢酶、NAD-linked enzymes）的抑制剂，还可与Bcl-xL 和 Bcl-2 结合。(Gossypol Acetic Acid is an inhibitor of some dehydrogenases such as lactate dehydrogenase, NAD-linked enzymes and can also bind to Bcl-xL and Bcl-2.)
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靶点
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Bcl-2 Family;Dehydrogenase
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通路
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Apoptosis;Metabolic Enzyme&Protease
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