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CAS
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465-21-4
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中文名称
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蟾毒灵
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英文名称
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Bufalin
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别名
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蟾酥灵
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纯度
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HPLC≥98%
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分子式
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C24H34O4
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分子量
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386.53
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00056525
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InChIKey
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QEEBRPGZBVVINN-BMPKRDENSA-N
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InChI
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InChI=1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19+,20-,22+,23-,24+/m1/s1
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PubChem CID
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9547215
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SMILES
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O[C@]([C@@](CC[C@@]1([H])[C@@]2(CC[C@H](O)C1)C)([H])[C@]2([H])CC3)(CC[C@@H]4C(C=C5)=COC5=O)[C@]34C
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描述
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蟾毒灵是重要蟾酥中的免疫活性成分,为有效的?Na+/K+-ATPase?抑制剂,可与Na+/K+-ATPase的亚基α1、α2和α3结合 α1, α2 和 α3 结合。(Bufalin is an important immunologically active ingredient in Bufonis bufa and is an effective Na+/K+-ATPase inhibitor, which can bind to subunits α1, α2 and α3 of Na+/K+-ATPase α1, α2 and α3.)
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靶点
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Na+/K+ ATPase
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通路
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Membrane Transporter&Ion Channel
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规格
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5mg 10mM*1mL (in DMSO) 10mg
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单位
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瓶
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