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CAS
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98-92-0
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中文名称
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烟酰胺
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英文名称
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Nicotinamide
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别名
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Nicotinic acid amide;Vitamin B3;Vitamin PP
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纯度
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HPLC≥98%
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分子式
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C6H6N2O
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分子量
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122.12
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water/DMSO ≥ 10mg/mL
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MDL
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MFCD00006395
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EC
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EINECS 202-713-4
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InChIKey
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DFPAKSUCGFBDDF-UHFFFAOYSA-N
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InChI
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InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
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PubChem CID
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936
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SMILES
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O=C(C1=CC=CN=C1)N
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描述
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Nicotinamide是一种B3维生素,通过促进NAD +氧化还原稳态和提供NAD +作为催化非氧化还原反应的一类酶的底物,在细胞生理学中发挥重要作用。是 SIRT1 的抑制剂。(Nicotinamide is a B3 vitamin that plays an important role in cellular physiology by promoting NAD+ redox homeostasis and providing NAD+ as a substrate for a class of enzymes that catalyze non-redox reactions. is an inhibitor of SIRT1.)
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靶点
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Sirtuin
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通路
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Cell Cycle;DNA Damage/DNA Repair; Epigenetics
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