CAS
|
61825-94-3
|
中文名称
|
奥沙利铂
|
英文名称
|
Oxaliplatin
|
别名
|
L-OHP
|
纯度
|
HPLC≥98%
|
分子式
|
C8H14N2O4Pt
|
分子量
|
397.29
|
外观(性状)
|
White to off-white Solid
|
储存条件
|
Powder : 2-8℃, 2 years
|
溶解性
|
(* 建议使用 DMF 而不是 DMSO溶解。* 该产品在溶液状态不稳定,建议您现用现配/*Use DMF instead of DMSO to dissolve.*The product is unstable after dissolution. It is recommended that you use it immediately after dissolution.)
|
MDL
|
MFCD00866327
|
EC
|
EINECS 621-248-1
|
InChIKey
|
DRMCATBEKSVAPL-BNTLRKBRSA-N
|
InChI
|
InChI=1S/C6H12N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-8H,1-4H2;(H,3,4)(H,5,6);/q-2;;+2/t5-,6-;;/m1../s1
|
PubChem CID
|
9887053
|
SMILES
|
O=C1[O-][Pt+2]2([NH2][C@@]3([H])[C@](CCCC3)([H])[NH2]2)[O-]C1=O
|
描述
|
(Oxaliplatin is a DNA synthesis inhibitor. Causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Can induce autophagy.)
|
靶点
|
Autophagy;DNA/RNA Synthesis
|
通路
|
Autophagy;Cell Cycle;DNA Damage/DNA Repair
|