|
CAS
|
58546-54-6
|
|
中文名称
|
五味子醇乙
|
|
英文名称
|
Schisandrol B
|
|
别名
|
Gomisin A;TJN-101;Wuweizi alcohol-B;Besigomsin;Gamma-Schisandrin
|
|
纯度
|
HPLC≥98%
|
|
分子式
|
C23H28O7
|
|
分子量
|
416.46
|
|
外观（性状）
|
White to off-white Solid
|
|
储存条件
|
Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
|
|
溶解性
|
Soluble in DMSO
|
|
MDL
|
MFCD01941645
|
|
InChIKey
|
ZWRRJEICIPUPHZ-UHFFFAOYSA-N
|
|
InChI
|
InChI=1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3
|
|
PubChem CID
|
634470
|
|
SMILES
|
O[C@@]([C@@H](C)C1)(C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC
|
|
描述
|
(Schisandrol B has antitumor activity.)
|
|
靶点
|
ROS;p-gp
|
|
通路
|
Immunology & Inflammation;Membrane Transporter&Ion Channel
|
|
生物活性
|
Schisandrol B (Gomisin-A) is a major active constituent of Schisandra sphenanthera with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities[1-3].
|
