|
CAS
|
2447-54-3
|
|
中文名称
|
血根碱
|
|
英文名称
|
Sanguinarine
|
|
别名
|
氯化血根碱; Dimethylenedioxy benzphenanthridine
|
|
纯度
|
HPLC≥98%
|
|
分子式
|
C20H14NO4
|
|
分子量
|
332.33
|
|
外观（性状）
|
Solid
|
|
储存条件
|
Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
|
|
溶解性
|
Soluble in DMSO
|
|
MDL
|
MFCD00064925
|
|
EC
|
EINECS 219-503-3
|
|
InChIKey
|
INVGWHRKADIJHF-UHFFFAOYSA-N
|
|
InChI
|
InChI=1S/C20H14NO4/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21/h2-8H,9-10H2,1H3/q+1
|
|
PubChem CID
|
5154
|
|
SMILES
|
C[N+]1=CC2=C3C(OCO3)=CC=C2C(C=CC4=C5)=C1C4=CC6=C5OCO6
|
|
描述
|
Sanguinarine 是一种生物碱，(Sanguinarine is an alkaloid that can stimulate cell apoptosis by activating the production of reactive oxygen species (ROS). Sanguinarine induced apoptosis and JNK and NF- κ B activation.)
|
|
靶点
|
Apoptosis;NF-KB
|
|
通路
|
Apoptosis;NF-κB
|
