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CAS
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149647-78-9
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中文名称
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伏立诺他
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英文名称
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Vorinostat
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别名
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异羟肟酸
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纯度
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HPLC≥98%
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分子式
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C14H20N2O3
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分子量
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264.32
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO ≥30mg/mL
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MDL
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MFCD00945317
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EC
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EINECS 682-505-1
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InChIKey
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WAEXFXRVDQXREF-UHFFFAOYSA-N
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InChI
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InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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PubChem CID
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5311
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SMILES
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O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O
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描述
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(Vorinostat is a potent HDAC inhibitor. Vorinostat can induce apoptosis. Vorinostat is also a potent inhibitor of human papillomavirus (HPV)-18 DNA amplification.)
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靶点
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HDAC
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通路
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DNA Damage/DNA Repair;Epigenetics;NF-κB
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