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CAS
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58-55-9
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中文名称
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茶碱
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英文名称
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Theophylline
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别名
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Theo-24;1，3-Dimethylxanthine
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纯度
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HPLC≥98%
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分子式
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C7H8N4O2
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分子量
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180.16
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in Water ≥ 5mg/mL
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MDL
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MFCD00079619
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EC
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EINECS 200-385-7
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InChIKey
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ZFXYFBGIUFBOJW-UHFFFAOYSA-N
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InChI
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InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
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PubChem CID
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2153
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SMILES
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O=C(N1C)N(C)C2=C(N=CN2)C1=O
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描述
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Theophylline是非选择性的磷酸二酯酶 (PDE)抑制剂,腺苷受体阻断剂,和组蛋白脱乙酰酶 (HDAC)活化剂。(Theophylline is a non-selective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.)
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靶点
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PDE;Adenosine Receptor;HDAC
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通路
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Metabolic Enzyme&Protease;GPCR & G Protein;DNA Damage/DNA Repair;Epigenetics;NF-κB
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