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CAS
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59-66-5
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中文名称
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乙酰唑胺
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英文名称
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Acetazolamide
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别名
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醋唑磺胺;Diamox
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纯度
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HPLC≥98%
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分子式
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C4H6N4O3S2
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分子量
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222.25
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外观（性状）
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White to off-white Solid
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO
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MDL
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MFCD00003105
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EC
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EINECS 200-440-5
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InChIKey
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BZKPWHYZMXOIDC-UHFFFAOYSA-N
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InChI
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InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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PubChem CID
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1986
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SMILES
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CC(NC1=NN=C(S(=O)(N)=O)S1)=O
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描述
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(It is a carbonic anhydrase inhibitor, inhibits carbonic anhydrase in renal tubular epithelial cells, reduces the formation of H2CO3, and reduces the production of H+.)
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靶点
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Carbonic Anhydrase
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通路
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Metabolic Enzyme&Protease
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生物活性
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Acetazolamide 是一种碳酸酐酶 (carbonic anhydrase, CA) IX 抑制剂[1]。
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IC50
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IC50 : 30 nM ( hCA IX) [1]
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