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大鼠骨形态发生蛋白1Elisa试剂盒
  • 品牌:Solarbio
  • 产地:国产
  • 型号:48T 96T
  • 货号:SEKR-0040
  • 发布日期: 2023-05-20
  • 更新日期: 2025-07-15
产品详请
产地 国产
品牌 Solarbio
货号 SEKR-0040
保存条件 2-8℃
用途 科研
包装规格 48T 96T
保质期 6个月
是否进口
中文名称 大鼠骨形态发生蛋白1Elisa试剂盒
储存条件 2-8℃
有效期 6个月
英文名称 Rat BMP1 Elisa Kit
英文别名 BMP-1; BMP1; Bone morphogenetic protein 1; Mammalian tolloid protein; mTld; OI13; PCOLC; PCP; PCP2; procollagen C-endopeptidase; Procollagen C-proteinase; procollagen C-proteinase 3; TLD
反应性 Rat
样品类型 血清/血浆/细胞培养上清
检测范围 25 - 1600 pg/ml
灵敏度 5 pg/ml
背景 Bone morphogenetic protein 1 (BMP-1), also known as procollagen C-proteinase (PCP), is a zinc protease of the astacin family. BMP-1/PCP plays a key role in formation of extracellular matrix (ECM) by converting precursor proteins into their mature and functional forms. The precursor proteins identified as substrates for BMP-1/PCP include collagens, biglycan, laminin 5, dentin matrix protein-1, and lysyl oxidase. There are six alternatively spliced forms known to be derived from the BMP-1 gene, and isoform 1 consisting of residues 1 to 730 was expressed. The secreted and purified protein does not contain the signal peptide (amino acid residues 1?22) and pro domain (residues 23?120), but contain protease (residues 121?321), CUB I (residues 322?434), CUB II (residues 435?546), EGF-like (residues 547?588) and CUB III (residues 591?703) domains. The pro domain is apparently cleaved by a furin-like proprotein convertase. The purified BMP-1/PCP is an active protease and its peptidase activity can be determined as described above. The purified BMP-1/PCP is predicted to possess procollagen C-proteinase activity because it contains the minimal domain structure required.
单位
规格 48T 96T
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