CAS
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61135-33-9
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中文名称
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5-乙炔基-2'-脱氧尿苷
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英文名称
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5-Ethynyl-2'-deoxyuridine
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别名
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EdU
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纯度
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≥98%
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分子式
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C11H12N2O5
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分子量
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252.22
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外观(性状)
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White to yellow Soild
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储存条件
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Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months
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溶解性
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Soluble in DMSO ≥5mg/mL(Need ultrasonic)
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MDL
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MFCD01675687
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描述
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5-Ethynyl-2'-deoxyuridine(EdU)是一种胸腺嘧啶核苷类似物,在细胞增殖时能够插入正在复制的 DNA 分子中,随后EdU与荧光叠氮化物在铜催化下产生的[3 + 2]环加成反应,可被用于开发为检测DNA合成的方法。还是一种基于烷基链的 PROTAC linker,可用于PROTAC的合成。(5-Ethynyl-2'-deoxyuridine(EdU) is a thymidine nucleoside analogues capable of insertion into DNA molecules being replicated during cell proliferation, and the subsequent [3 + 2] cycloaddition reaction of EdU with fluorescent azide catalyzed by copper can be developed as a method for detecting DNA synthesis. It is also an alkyl chain based PROTAC linker that can be used in PROTAC synthesis.)
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靶点
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Others
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通路
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Others
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规格
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50mg
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单位
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瓶
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