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英文名称 | Recombinant Human BD-3 |
包装规格 | 5µg/20µg |
纯度 | % |
CAS编号 | |
别名 | 仅供科研使用 |
分子式 |
peprotech 300-52重组人β-防御素3价格,原装细胞因子peprotech现货价格
300-52
Synonyms:
Beta-Defensin 3, DEFB3, DEFB103A
Description:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.
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